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The relationship between P-wave dispersion and diastolic functions in diabetic children

Reşit Köken1, Tevfik Demir, Tolga Altuğ Sen

  • 1Department of Pediatrics, Medical Faculty, Kocatepe University, Afyonkarahisar, Turkey. resitkoken@hotmail.com

Cardiology in the Young
|March 13, 2010
PubMed

Insights

Type 1 diabetes negatively affects diastolic function in children, alongside increased P-wave dispersion. However, no direct link was found between P-wave dispersion and diastolic dysfunction in these young patients.

Area of Science:

  • Cardiology
  • Pediatrics
  • Endocrinology

Background:

  • Type 1 diabetes (T1D) is a chronic condition affecting children.
  • Diabetic complications can impact cardiovascular health.
  • P-wave dispersion and diastolic function are key indicators of cardiac health.

Purpose of the Study:

  • To investigate the relationship between P-wave dispersion and diastolic function in children with T1D.
  • To assess cardiac involvement in pediatric T1D patients.

Main Methods:

  • Echocardiography was used to evaluate left and right ventricular diastolic functions.
  • P-wave dispersion was calculated from surface electrocardiogram measurements.
  • 33 T1D children and 29 healthy controls were included.

Main Results:

  • Diabetic children showed significantly increased P-wave maximum duration and dispersion compared to controls.
  • Mitral A velocity and tricuspid A velocity time integral were elevated in diabetics.
  • Tricuspid deceleration time was significantly lower in diabetic children.

Conclusions:

  • Diastolic function of both ventricles is negatively affected in children with T1D.
  • Diabetes may contribute to prolonged P-wave dispersion.
  • No correlation was found between P-wave dispersion and diastolic function in this cohort.
Abstract

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