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Viral hepatitis

Geraldine M McQuillian1, Deanna Kruszon-Moran, Maxine M Denniston

  • 1Centers for Disease Control and Prevention National Center for Health Statistics 3311 Toledo Road, Hyattsville, Maryland 20782, USA.

NCHS Data Brief
|March 13, 2010
PubMed

Insights

Hepatitis A immunity increased in US-born children but decreased in older adults. Hepatitis B vaccination rates are high, and Hepatitis C infection prevalence has declined, though it remains higher in non-Hispanic Black populations.

Area of Science:

  • Epidemiology
  • Infectious Diseases
  • Public Health

Background:

  • Viral hepatitis poses a significant public health challenge.
  • Understanding trends in hepatitis A, B, and C prevalence is crucial for targeted interventions.

Purpose of the Study:

  • To analyze recent trends in the prevalence of hepatitis A, B, and C infections and immunity in the United States.
  • To identify demographic shifts in infection rates and vaccination coverage.

Main Methods:

  • Analysis of seroprevalence data for hepatitis A, B, and C.
  • Examination of vaccination records for hepatitis B vaccine.
  • Stratification of data by age, sex, and race/ethnicity.

Main Results:

  • Hepatitis A antibody prevalence increased in US-born individuals aged 6-19, while decreasing in those 40 and older.
  • Hepatitis B virus (HBV) infection decreased in children aged 6-19, with over 90% receiving the vaccine by 2003-2006.
  • Hepatitis C virus (HCV) infection prevalence declined among high-risk groups, but remains higher in non-Hispanic Black populations, with a peak prevalence shift to those aged 40-49.

Conclusions:

  • Vaccination programs have impacted HBV infection rates in younger populations.
  • Shifting demographics of HCV infection highlight the need for continued surveillance and targeted prevention strategies.
  • Age-related trends in hepatitis A immunity suggest waning immunity in older cohorts.
Abstract

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