Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Toroids01:27

Toroids

A toroid is a closely wound donut-shaped coil constructed using a single conducting wire. In general, it is assumed that a toriod consists of multiple circular loops perpendicular to its axis.
When connected to a supply, the magnetic field generated in the toroid has field lines circular and concentric to its axis. Conventionally, the direction of this magnetic field is expressed using the right-hand rule. If the fingers of the right hand curl in the current direction, the thumb points in the...
Equivalent Couples01:28

Equivalent Couples

In mechanical engineering, the concept of equivalent couples plays a crucial role in understanding and analyzing various mechanical systems.
Two couples are considered to be equivalent if they produce the same rotational effect on a rigid body. In other words, the two couples have the same magnitude and act in the same direction, causing the same angular displacement or acceleration in the body.
For instance, consider two couples lying in the plane of the page, with one having a pair of equal...
Parallel-axis Theorem01:06

Parallel-axis Theorem

The parallel-axis theorem provides a convenient and quick method of finding the moment of inertia of an object about an axis parallel to the axis passing through its center of mass. Consider a thin rod as an example. There is a striking similarity between the process of finding the moment of inertia of a thin rod about an axis through its middle, where the center of mass lies, and about an axis through its end using the conventional method. In the conventional method, the concept of linear mass...
Spin–Spin Coupling: Two-Bond Coupling (Geminal Coupling)01:20

Spin–Spin Coupling: Two-Bond Coupling (Geminal Coupling)

Two NMR-active nuclei bonded to a central atom can be involved in geminal or two-bond coupling. Geminal coupling is commonly seen between diastereotopic protons in chiral molecules and unsymmetrical alkenes, among others.
The central atom need not be NMR-active because its electrons are affected by the electron polarization of the spin-active atoms. However, spin information is transmitted less effectively than in one-bond coupling, and 2J values are usually weaker than 1J values. The energy of...
Trihybrid Crosses02:27

Trihybrid Crosses

Trihybrid Crosses
Some of Mendel’s crosses examined three pairs of contrasting characteristics. Such a cross is called a trihybrid cross. A trihybrid cross is a combination of three individual monohybrid crosses. For example, plant height (tall vs. short), seed shape (round vs. wrinkled), and seed color (yellow vs. green).
The F1 generation plants of a trihybrid cross are heterozygous for all three traits and produce eight gametes. Upon self-fertilization, these gametes have an equal chance to...
Symmetry01:26

Symmetry

The equation of an ellipse centered at the origin defines all points whose distances from the center maintain a constant ratio between the horizontal and vertical axes. This equation results in a smooth, closed curve that extends further along the x-axis than the y-axis, giving it a horizontal orientation. Such an ellipse demonstrates three kinds of symmetry: across the x-axis, across the y-axis, and about the origin. These symmetries are essential in understanding the graph's structure and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cracking the (zip)code of dynein-dependent RNA localization.

Nature structural & molecular biology·2026
Same author

Decoding the interactions and functions of non-coding RNA with artificial intelligence.

Nature reviews. Molecular cell biology·2025
Same author

m6A modification inhibits miRNAs' intracellular function, favoring their extracellular export for intercellular communication.

Cell reports·2024
Same author

m6a methylation orchestrates IMP1 regulation of microtubules during human neuronal differentiation.

Nature communications·2024
Same author

From the Operating Room to the Laboratory: Role of the Neuroscience Tissue Biorepository in the Clinical, Translational, and Basic Science Research Pipeline.

Mayo Clinic proceedings·2024
Same author

Development of a specific and potent IGF2BP1 inhibitor: A promising therapeutic agent for IGF2BP1-expressing cancers.

European journal of medicinal chemistry·2023
Same journal

Identification and structure determination of a type III-Bv CRISPR complex that post-translationally modifies an associated toxin.

Structure (London, England : 1993)·2026
Same journal

Cryo-EM structure of the Arabidopsisthaliana ribosome in translating and non-translating states.

Structure (London, England : 1993)·2026
Same journal

Multifaceted effects of N-glycosylation on amyloidogenic κ light chains in AL amyloidosis.

Structure (London, England : 1993)·2026
Same journal

Near-complete cryo-EM structure of the Klebsiella pneumoniae podophage RAN69 reveals tail fiber-spike interface and a divergent pre-ejectosome.

Structure (London, England : 1993)·2026
Same journal

Saxiphilin is a broad-spectrum toxin sponge for C13-modified saxitoxins.

Structure (London, England : 1993)·2026
Same journal

Cryo-EM structure of YfdQ reveals a widespread family of bacteriophage-associated proteins with shell-like assemblies.

Structure (London, England : 1993)·2026
See all related articles

Related Experiment Video

Updated: Jun 15, 2026

Synthetic Condensates and Cell-Like Architectures from Amphiphilic DNA Nanostructures
08:02

Synthetic Condensates and Cell-Like Architectures from Amphiphilic DNA Nanostructures

Published on: May 31, 2024

Creating a twin STAR.

Cyprian D Cukier, Andres Ramos

    Structure (London, England : 1993)
    |March 13, 2010
    PubMed
    Summary
    This summary is machine-generated.

    The Signal Transduction and Activation of RNA (STAR) protein family regulates RNA metabolism by forming homodimers. The structure of GLD-1

    More Related Videos

    Accurate and Simple Evaluation of Vascular Anastomoses in Monochorionic Placenta using Colored Dye
    09:52

    Accurate and Simple Evaluation of Vascular Anastomoses in Monochorionic Placenta using Colored Dye

    Published on: September 5, 2011

    Cell Lineage Analyses and Gene Function Studies Using Twin-spot MARCM
    06:30

    Cell Lineage Analyses and Gene Function Studies Using Twin-spot MARCM

    Published on: March 2, 2017

    Related Experiment Videos

    Last Updated: Jun 15, 2026

    Synthetic Condensates and Cell-Like Architectures from Amphiphilic DNA Nanostructures
    08:02

    Synthetic Condensates and Cell-Like Architectures from Amphiphilic DNA Nanostructures

    Published on: May 31, 2024

    Accurate and Simple Evaluation of Vascular Anastomoses in Monochorionic Placenta using Colored Dye
    09:52

    Accurate and Simple Evaluation of Vascular Anastomoses in Monochorionic Placenta using Colored Dye

    Published on: September 5, 2011

    Cell Lineage Analyses and Gene Function Studies Using Twin-spot MARCM
    06:30

    Cell Lineage Analyses and Gene Function Studies Using Twin-spot MARCM

    Published on: March 2, 2017

    Area of Science:

    • Molecular Biology
    • Genetics
    • Biochemistry

    Background:

    • The Signal Transduction and Activation of RNA (STAR) protein family plays a crucial role in regulating RNA metabolism.
    • STAR proteins are known to function as homodimers, suggesting that dimerization is key to their biological activity.

    Discussion:

    • The recently elucidated structure of the QUA1 dimerization domain of the GLD-1 protein provides critical insights into the mechanism of STAR protein homodimerization.
    • This structural information establishes a direct link between the homodimeric state of STAR proteins and their ability to recognize and bind specific RNA targets.

    Key Insights:

    • STAR protein homodimerization is a key regulatory mechanism in RNA metabolism.
    • The GLD-1 QUA1 domain structure reveals how dimerization interfaces with RNA recognition.
    • Understanding STAR protein structure-function relationships is essential for deciphering RNA regulation pathways.

    Outlook:

    • Further structural and biochemical studies of other STAR proteins will likely reveal conserved dimerization principles.
    • This knowledge can inform the development of novel therapeutic strategies targeting RNA metabolism dysregulation.
    • Investigating the dynamic aspects of STAR protein dimerization and RNA binding will be crucial for a complete understanding.