Related Experiment Video
Updated: Oct 13, 2026
08:09
Peptide Scanning-assisted Identification of a Monoclonal Antibody-recognized Linear B-cell Epitope
Published on: March 24, 2017
Extended nucleotide sequence of the switch region of the murine gene encoding immunoglobulin E
L A Scappino1, C Chu, C A Gritzmacher
1Medical Biology Institute, La Jolla, CA 92037.
Gene
|March 15, 1991
Abstract:
The nucleotide sequence of the switch region (S epsilon) of the gene encoding murine IgE was determined from a germline DNA clone. The sequence extends 1.7 kb 5' to the previously published S epsilon sequence. Another 33 repeat units were located by comparison to the S epsilon consensus sequence. Therefore, the complete S epsilon repetitive sequence consists of 53 repeat units contained in a region about 2.5 kb long.
Related Concept Videos
02:02Cis-regulatory Sequences
Cis-regulatory sequences are short fragments of non-coding DNA that are present on the same chromosomes as the genes that they regulate. These fragments serve as binding sites for transcriptional regulators, proteins that are responsible for controlling gene transcription and differential gene expression across cell types in eukaryotes. Cis-regulatory sequences can be close to the gene of interest or thousands of bases away in the DNA sequence; however, those sequences that are further away are...
02:02Cis-regulatory Sequences
Cis-regulatory sequences are short fragments of non-coding DNA that are present on the same chromosomes as the genes that they regulate. These fragments serve as binding sites for transcriptional regulators, proteins that are responsible for controlling gene transcription and differential gene expression across cell types in eukaryotes. Cis-regulatory sequences can be close to the gene of interest or thousands of bases away in the DNA sequence; however, those sequences that are further away are...