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Extended nucleotide sequence of the switch region of the murine gene encoding immunoglobulin E
L A Scappino1, C Chu, C A Gritzmacher
1Medical Biology Institute, La Jolla, CA 92037.
Gene
|March 15, 1991
Abstract:
The nucleotide sequence of the switch region (S epsilon) of the gene encoding murine IgE was determined from a germline DNA clone. The sequence extends 1.7 kb 5' to the previously published S epsilon sequence. Another 33 repeat units were located by comparison to the S epsilon consensus sequence. Therefore, the complete S epsilon repetitive sequence consists of 53 repeat units contained in a region about 2.5 kb long.