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CREB's control of intrinsic and synaptic plasticity: implications for CREB-dependent memory models

Eva Benito1, Angel Barco

  • 1Instituto de Neurociencias de Alicante (Universidad Miguel Hernández-Consejo Superior de Investigaciones Científicas), Campus de Sant Joan, Apt. 18, Sant Joan d'Alacant, 03550, Alicante, Spain.

Trends in Neurosciences
|March 13, 2010
PubMed
Summary

The cAMP-response element binding protein (CREB) is vital for long-term memory formation by influencing gene expression. New findings show CREB also affects neuron excitability, linking intrinsic and synaptic plasticity in memory.

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