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Updated: Jun 15, 2026

Genome-wide Surveillance of Transcription Errors in Eukaryotic Organisms
Published on: September 13, 2018
An algorithm for the reconstruction of consensus sequences of ancient segmental duplications and transposon copies in
Abanish Singh1, Umeshkumar Keswani, David Levine
1Department of Computer Science and Engineering, University of Texas, Arlington, TX 76019, USA. abanish.singh@mavs.uta.edu
Abstract:
Interspersed repeats, mostly resulting from the activity and accumulation of transposable elements, occupy a significant fraction of many eukaryotic genomes. More than half of human genomic sequence consists of known repeats, however a very large part has not yet been associated with neither repetitive structures nor functional units. We have postulated that most of the seemingly unique content of mammalian genomes is also a result of transposon activity, written software to look for weak signals which would help us reconstruct the ancient elements with substantially mutated copies, and integrated it into a system for de novo identification and classification of interspersed repeats. In this manuscript we describe our approach, and report on our methods for building the consensus sequences of these transposons.
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