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Updated: Jun 15, 2026
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Rat Model of Adhesive Capsulitis of the Shoulder
Published on: September 28, 2018
Increased risk of stroke after adhesive capsulitis: a population-based study
Jiunn-Horng Kang1, Jau-Jiuan Sheu, Herng-Ching Lin
1Department of Physical Medicine and Rehabilitation and Neuroscience Research Center, Taipei Medical University Hospital, Taipei, Taiwan.
Stroke
|March 13, 2010
Summary
Individuals with adhesive capsulitis (AC) face a higher risk of stroke. This study found a significant association, highlighting the need for further investigation into the underlying mechanisms and potential preventative strategies.
Area of Science:
- Medical research
- Epidemiology
- Neurology
Background:
- Adhesive capsulitis (AC), commonly known as frozen shoulder, has no previously established link to stroke risk.
- Understanding potential comorbidities and associated health risks is crucial for comprehensive patient care.
Purpose of the Study:
- To investigate the association between a history of adhesive capsulitis and the subsequent risk of stroke.
- To determine if AC is an independent risk factor for stroke using population-based data.
Main Methods:
- A population-based study comparing 10,935 patients diagnosed with AC to 32,805 randomly selected controls.
- Utilized log-rank tests and Cox proportional hazard regressions to analyze stroke-free survival and hazard ratios.
- Data collected between 2000 and 2003.
Main Results:
- Patients with AC had a higher incidence of stroke (5.3%) compared to controls (3.7%).
- The crude hazard ratio for stroke in the AC group was 1.46 (95% CI, 1.32-1.62; P<0.001).
- The adjusted hazard ratio for stroke remained significantly elevated at 1.22 (95% CI, 1.06-1.40; P=0.002).
Conclusions:
- Adhesive capsulitis is associated with an increased prevalence and risk of stroke.
- Further research is warranted to validate these findings and elucidate the biological mechanisms connecting AC and stroke.
- This suggests a potential need for increased stroke surveillance in patients with AC.
