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Updated: Jun 15, 2026
Assays for the Identification of Novel Antivirals against Bluetongue Virus
Published on: October 11, 2013
A rapid assay for detecting antibody against Bluetongue virus with a latex agglutination test using recombinant VP7
Junxing Yang1, Qunyi Hua, Huanchun Chen
1No. 2049, Heping Road, Shenzhen, Guangdong, P. R. China 518001. ciqhua@yahoo.com.cn
Abstract:
A latex agglutination test (LAT) for detecting antibody against Bluetongue virus (BTV) in ruminants was developed using latex beads coupled with recombinant VP7 protein. Compared with competitive enzyme-linked immunosorbent assay (ELISA), the specificity and sensitivity of the LAT were 99.0% and 93.0%, respectively. There was excellent agreement between the results obtained by competitive ELISA and the LAT (kappa = 0.930). Because it is rapid and easy to use, the LAT could be used for BTV antibody detection, especially for screening many serum samples.
