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Updated: Jun 15, 2026
07:49
Measuring Local Anaphylaxis in Mice
Published on: October 14, 2014
[Patent blue V : inert dye or potent allergen]
V Rogler1, C Röhm, J Reutershan
1Klinik für Anaesthesiologie und Intensivmedizin, Universitätsklinikum Tübingen, Hoppe-Seyler-Str. 3, 72076 Tübingen, Deutschland.
Der Anaesthesist
|March 13, 2010
Summary
Severe anaphylactic shock can occur from Patent Blue V, a dye used in oncological surgery. This case highlights diagnostic challenges and anesthetic management for this rare but serious adverse event.
Area of Science:
- Oncology
- Anesthesiology
- Clinical Pathology
Background:
- Patent Blue V is a widely used food dye.
- Its clinical application has expanded to oncological surgery for sentinel lymph node identification in various cancers.
- Sentinel lymph node biopsy aids in cancer staging and treatment planning.
Observation:
- A patient undergoing breast cancer surgery experienced severe anaphylactic shock following a subcutaneous injection of Patent Blue V.
- The dye is essential for visualizing lymphatic pathways during surgery.
- Immediate recognition and management of anaphylaxis are critical.
Findings:
- The study presents a case of severe anaphylactic shock attributed to Patent Blue V during oncological surgery.
- It details the clinical presentation and the anesthesiological interventions employed.
- Potential delays in diagnosis due to atypical presentations are discussed.
Implications:
- Anesthesiologists and surgeons must be aware of the risk of anaphylaxis from Patent Blue V.
- Prompt diagnosis and management are crucial for patient safety.
- This case underscores the importance of preparedness for adverse reactions to surgical dyes.
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