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Detergent Purification of Membrane Proteins

Detergents are used to purify the integral proteins of the membrane. The hydrophobic portion of the detergent can replace membrane phospholipids while solubilizing the membrane proteins. When detergent monomers reach a specific concentration in a solution called critical micelle concentration (CMC), they form micelles. Above CMC, the concentration of the detergent monomers remains in equilibrium with the micelle. The number of detergent monomers present in the CMC varies for each detergent, and...

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Welcome to mobile DNA

Nancy L Craig1, Thomas H Eickbush, Daniel F Voytas

  • 1Department of Molecular Biology & Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. ncraig@jhmi.edu.

Mobile DNA
|March 16, 2010
PubMed
Summary

No abstract available in PubMed .

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