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Published on: February 22, 2019
Mumps vaccine effectiveness in highly immunized populations
Angela Domínguez1, Núria Torner, Jesús Castilla
1Department of Public Health, University of Barcelona, Casanova 143, 08036, Barcelona, Spain. angela.dominguez@ub.edu
Vaccine
|March 16, 2010
Summary
This study found that the measles, mumps, and rubella (MMR) vaccine is highly effective against mumps, even in highly vaccinated populations. Achieving higher two-dose MMR coverage is crucial for preventing future mumps outbreaks.
Area of Science:
- * Public Health
- * Epidemiology
- * Immunization
Background:
- * Mumps outbreaks continue to occur in communities with high measles, mumps, and rubella (MMR) vaccine coverage.
- * Understanding vaccine effectiveness (VE) is crucial for refining public health strategies.
Purpose of the Study:
- * To investigate the effectiveness of the mumps component of the MMR vaccine during outbreaks in areas with high MMR coverage.
- * To evaluate VE based on the number of MMR vaccine doses received.
Main Methods:
- * Retrospective study of mumps cases reported to public health services in Navarre and Catalonia (2005-2007).
- * Cases born between 1995 and 2005 were analyzed.
- * Vaccine effectiveness was calculated using the screening method.
Main Results:
- * Of 47 confirmed mumps cases, 85.1% had received at least one dose (1MMR) and 44.9% had received two doses (2MMR).
- * Estimated VE for 1MMR was 85.4% (95% CI: 67.3-93.4).
- * Estimated VE for 2MMR was 88.5% (95% CI: 78.1-93.9).
Conclusions:
- * The MMR vaccine demonstrates high effectiveness against mumps, even in highly vaccinated populations.
- * Increased two-dose MMR coverage is recommended to prevent future mumps outbreaks.
- * Further research on VE using all confirmed cases and improved confirmation techniques is warranted.
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