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Coronary blood flow and perfusion pressure during coronary angiography in patients with ongoing mechanical chest

Alf Inge Larsen1, Ashild Hjørnevik, Vernon Bonarjee

  • 1Department of Cardiology, Stavanger University Hospital, Stavanger, Norway; University of Bergen, Institute of Internal Medicine, Norway. alfil@broadpark.no

Resuscitation
|March 16, 2010
PubMed

Insights

The LUCAS chest compression device may support coronary circulation during cardiac arrest procedures. In some patients, it enabled satisfactory coronary perfusion pressure and blood flow, aiding survival.

Area of Science:

  • Cardiology
  • Emergency Medicine
  • Medical Devices

Background:

  • Patients with pulseless electrical activity or refractory ventricular fibrillation face poor prognoses.
  • Restoring circulation via coronary angiography and angioplasty during ongoing chest compressions is critical.
  • The LUCAS (Low Unique Chest Assistance System) device is designed for mechanical chest compressions during such interventions.

Observation:

  • This study investigated the effect of the LUCAS device on human coronary circulation.
  • Coronary perfusion pressure (CPP) and coronary blood flow (TIMI scale) were invasively monitored in 6 patients undergoing CPR.
  • The LUCAS device was used to maintain chest compressions during cardiac catheterization.

Findings:

  • Four out of six patients demonstrated satisfactory coronary artery perfusion pressure and TIMI grade 3 flow (normal) during LUCAS device use.
  • Two of these patients survived the initial 24 hours post-procedure.
  • The remaining two patients did not achieve adequate perfusion pressure or flow rates.

Implications:

  • The LUCAS device appears to facilitate adequate coronary circulation in a subset of patients with cardiac arrest undergoing PCI.
  • This suggests potential benefits for using mechanical chest compression devices during interventional procedures for critical cardiac events.
  • Further research is warranted to optimize device use and patient selection for improved outcomes.

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