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Related Concept Videos

Development of the Limb Synovial Joints01:07

Development of the Limb Synovial Joints

Joints form during embryonic development in conjunction with the formation and growth of the associated bones. The embryonic tissue that gives rise to all bones, cartilage, and connective tissues of the body is called mesenchyme.
The mesenchymal stem cells differentiate into chondrocytes that form the hyaline cartilage, and later the cartilaginous model of the bone. This model further transforms into a bone. This process is known as endochondral ossification.
During development, the limbs...
Structural Joints: Synovial Joints01:16

Structural Joints: Synovial Joints

Synovial joints are the most common type of joint in the body. A key structural characteristic for a synovial joint is the presence of a joint cavity. This fluid-filled space is where the articulating surfaces of the bones contact each other. Also, unlike fibrous or cartilaginous joints, the articulating bone surfaces at a synovial joint are not directly connected to each other with fibrous connective tissue or cartilage. This gives the bones of a synovial joint the ability to move smoothly...
Bone Formation by Endochondral Ossification01:24

Bone Formation by Endochondral Ossification

Bone formation, or ossification, begins around the sixth to seventh week of embryonic development. Most bones develop from a cartilaginous template through the process of endochondral ossification. Cartilage formation begins when clusters of mesenchymal cells differentiate into chondrocytes. These chondrocytes proliferate rapidly and secrete an extracellular matrix that becomes encased in a membrane called the perichondrium. The resulting cartilage model provides a template that resembles the...
Bones of the Upper Limb: Humerus01:19

Bones of the Upper Limb: Humerus

The upper limb consists of the arm, forearm, wrist, and hand bones. The humerus is the single bone of the upper arm region. Proximally, it has a large, spherical, smooth head that articulates with the glenoid cavity of the scapula to form the glenohumeral or shoulder joint. The margin of the head is the anatomical neck, a residual epiphyseal plate. Laterally it extends to form bony projections called the greater tubercle and the lesser tubercle. Next to the tubercles is the surgical neck, a...
Bone Disorders01:29

Bone Disorders

Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bones of the Upper Limb: Ulna01:15

Bones of the Upper Limb: Ulna

The ulna and radius are parallel bones of the antebrachium or the forearm. The ulna lies medially and consists of a bony tip called the olecranon process at its proximal end. This hook-like projection articulates with the olecranon fossa of the humerus and forms the "hinged" ulnohumeral part of the elbow joint. This joint facilitates forearm extension and flexion while preventing its hyperextension. Similarly, the coronoid process, another bony projection on the proximal/anterior side of the...

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Related Experiment Videos

Solitary synovial osteochondroma.

Emanuela Veras1, Rania Abadeer, Hema Khurana

  • 1Department of Pathology, Memorial-Sloan Kettering Cancer Center, New York, NY 10065, USA. emanuelafveras@gmail.com

Annals of Diagnostic Pathology
|March 16, 2010
PubMed
Summary

Solitary synovial osteochondroma (SSO) is a rare tumor that can mimic chondrosarcoma. Accurate diagnosis requires careful radiographic and clinicopathologic analysis for effective treatment.

Related Experiment Videos

Area of Science:

  • Orthopedics
  • Pathology
  • Radiology

Background:

  • Solitary synovial osteochondroma (SSO) is an uncommon extraskeletal osteochondroma.
  • Understanding its clinicopathologic and radiographic features is crucial for diagnosis.

Observation:

  • Reviewed 5 cases of SSO, focusing on clinical, radiographic, and histopathologic data.
  • Patient ages ranged from 33-63 years, with knee masses being the most common presentation.
  • Histopathology revealed lobulated hyaline cartilage with calcification; one case showed cytologic atypia without malignancy.

Findings:

  • SSO presented as well-circumscribed masses with cartilaginous lobules.
  • Radiographic studies in two cases suggested chondrosarcoma.
  • Surgical excision was curative in cases with available follow-up.

Implications:

  • SSO is a rare lesion that can be mistaken for low-grade chondrosarcoma.
  • Distinguishing SSO from malignancy relies on integrated radiographic and clinicopathologic assessment.
  • Accurate diagnosis ensures appropriate patient management and surgical outcomes.