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Updated: Jun 15, 2026

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
Published on: December 11, 2017
Cardiac resynchronization therapy after atrioventricular node ablation for rapid atrial fibrillation in a heart
Justin A Mariani1, Michael A McDonald, Kumaraswamy Nanthakumar
1Division of Cardiology, Peter Munk Cardiac Centre, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada. justin.mariani@utoronto.ca
Abstract:
We report the successful use of cardiac resynchronization therapy in an orthotopic heart transplant recipient with late graft dysfunction, severe heart failure, and atrial fibrillation requiring atrioventricular node ablation. This case highlights the potential role for cardiac resynchronization therapy in orthotopic heart transplant recipients with systolic dysfunction and heart failure, especially in the setting of forced right ventricular pacing. Despite potentially different mechanisms of left ventricular dysfunction, biventricular pacing should be considered for allograft recipients with conventional indications for cardiac resynchronization therapy.
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