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Non-invasive Imaging of Acute Allograft Rejection after Rat Renal Transplantation Using 18F-FDG PET
Published on: April 28, 2013
Feline renal allograft rupture
Carrie A Palm1, Lillian R Aronson, Philipp D Mayhew
1University of Pennsylvania, School of Veterinary Medicine, Department of Clinical Studies, Philadelphia, PA 19104, USA. capalm77@gmail.com
Journal of Feline Medicine and Surgery
|March 16, 2010
Summary
A cat experienced renal allograft rupture and hemorrhage three months post-transplantation, leading to fatal complications. This case highlights a rare but severe complication in feline renal transplantation.
Area of Science:
- Veterinary Medicine
- Nephrology
- Transplantation Surgery
Background:
- Renal transplantation in cats is a complex procedure aimed at managing end-stage renal disease.
- Graft survival and complications are critical aspects of post-transplant care.
Observation:
- A 5-year-old domestic shorthair cat presented with abdominal discomfort three months after renal allograft transplantation.
- Ultrasound revealed an enlarged renal allograft with pyelectasia, ureteral and urethral dilation, and abdominal effusion.
- The cat became hemodynamically unstable, diagnosed with hemoabdomen due to a sub-capsular hematoma.
Findings:
- Emergency laparotomy identified cortical ruptures in the transplanted kidney as the source of hemorrhage.
- Histopathology confirmed renal allograft rupture.
- This represents the first reported case of renal allograft rupture in a feline patient.
Implications:
- Renal allograft rupture is a critical, potentially fatal complication following kidney transplantation in cats.
- This case underscores the importance of vigilant monitoring for rare complications in feline transplant recipients.
- Further research into risk factors and prevention strategies for allograft rupture in cats is warranted.

