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Updated: Jun 15, 2026

Imaging the Human Immunological Synapse
Published on: December 26, 2019
What is an immunological synapse?
José Luis Rodríguez-Fernández1, Lorena Riol-Blanco, Cristina Delgado-Martín
1Centro de Investigaciones Biológicas, Consejo Superior de Investigaciones Científicas, 28040 Madrid, Spain. rodrifer@cib.csic.es
Immunological synapses (IS) are emerging as highly organized 3D structures -formed by surface and cytoplasmic signalling and cytoskeletal molecules - that assemble at the zone of contact between a T cell and an antigen presenting cell (APC). The IS control functions that allow APC and T cells modulate the immune response.
Immunological synapses (IS) are emerging as highly organized 3D structures -formed by surface and cytoplasmic signalling and cytoskeletal molecules - that assemble at the zone of contact between a T cell and an antigen presenting cell (APC). The IS control functions that allow APC and T cells modulate the immune response.
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