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Clinical pharmacokinetics and interaction of centchroman--a mini review

Jawahar Lal1

  • 1Pharmacokinetics and Metabolism Division, Central Drug Research Institute, CSIR, Lucknow, India. jlalcdri@rediffmail.com

Contraception
|March 16, 2010
PubMed

This article provides a brief review of the information available regarding the published pharmacokinetics data for the nonsteroidal, once-a-week oral contraceptive, centchroman (INN: ormeloxifene). This agent is a unique need-oriented contraceptive agent which is included in the National Family Welfare Programme of India. Since 1991, centchroman has been used as a need-oriented contraceptive and is being given for treating dysfunctional bleeding of the uterus. Information regarding absorption, tissue distribution, elimination and kinetic interactions is discussed.

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