Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Herniated Intervertebral Disc l: Introduction

Herniated Intervertebral Disc l: Introduction

Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...

Local Anesthetics: Clinical Application as Spinal Anesthesia

Local Anesthetics: Clinical Application as Spinal Anesthesia

Spinal anesthetics are given during lower abdomen and limb surgeries to block sensory and motor neurons. They are administered in the mid to low lumbar regions, primarily acting on the cauda equina's nerve roots. The blockade level depends on the local anesthetic (LA) concentration. Usually, low LA concentrations are sufficient to block sensory fibers, while only high LA concentrations block motor fibers. Other factors like injection volume and speed, the patient's posture, and the drug...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Implementing Systems-Based Interventions to Improve the Care of Cancer Survivors: Small Steps, Large Challenges.

JCO oncology practice·2026

Same author

Investigating the effects of conservative treatments on the flexion relaxation phenomenon for chronic low back pain: A systematic review.

Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology·2026

Same author

Comment on "BMJ Publications on Interventional Techniques Do Not Meet Appropriateness Criteria of Conducting a Rapid Review: A Comprehensive Review".

Pain physician·2026

Same author

Can Implementing Guideline-Recommended Care Prevent Chronic Low Back Pain?

JAMA internal medicine·2026

Same author

CLIN-SUMM: Incremental Longitudinal Summarization of Clinical Notes Enables Scalable Representation and Early Disease Prediction.

medRxiv : the preprint server for health sciences·2026

Same author

Exploring the Lack of Concordance between the Preferred and Actual Approach to Colorectal Cancer Screening in Older Adults: A Qualitative Study.

Medical decision making : an international journal of the Society for Medical Decision Making·2026

Same journal

The young adult with Juvenile Idiopathic Arthritis (JIA): A clinical review of transition, complications, and psychosocial management.

Best practice & research. Clinical rheumatology·2026

Same journal

Impact of fatigue on rheumatic diseases: Current perspectives.

Best practice & research. Clinical rheumatology·2026

Same journal

Pneumocystis prophylaxis in rheumatic disease.

Best practice & research. Clinical rheumatology·2026

Same journal

Cutaneous manifestations in myositis syndromes.

Best practice & research. Clinical rheumatology·2026

Same journal

Systemic sclerosis: A comprehensive systematic review of global epidemiology, sex and ethnic disparities, disease burden, and organ-specific involvement.

Best practice & research. Clinical rheumatology·2026

Same journal

Alopecia across the spectrum of rheumatic disease.

Best practice & research. Clinical rheumatology·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 15, 2026

Percutaneous Endoscopic Unilateral-Approach Bilateral Decompression for Lumbar Spinal Stenosis

Percutaneous Endoscopic Unilateral-Approach Bilateral Decompression for Lumbar Spinal Stenosis

Published on: February 9, 2024

Lumbar spinal stenosis.

Stephane Genevay¹, Steven J Atlas

¹Division of Rheumatology, University Hospitals of Geneva, Geneva, Switzerland. stephane.genevay@hcuge.ch

Best Practice & Research. Clinical Rheumatology

|March 16, 2010

Summary

This summary is machine-generated.

Lumbar spinal stenosis (LSS) is increasingly diagnosed in older adults due to degenerative changes. Decompressive laminectomy is supported for persistent symptoms, emphasizing shared decision-making for treatment choices.

More Related Videos

The Third Channel-Assisted Unilateral Biportal Endoscopic Technique for Lumbar Spinal Stenosis Combined with Contralateral Disc Herniation

The Third Channel-Assisted Unilateral Biportal Endoscopic Technique for Lumbar Spinal Stenosis Combined with Contralateral Disc Herniation

Published on: November 17, 2023

Full-Endoscopic Interlaminar Approach for Decompression of Lateral Recess Stenosis

Full-Endoscopic Interlaminar Approach for Decompression of Lateral Recess Stenosis

Published on: February 24, 2023

Related Experiment Videos

Last Updated: Jun 15, 2026

Percutaneous Endoscopic Unilateral-Approach Bilateral Decompression for Lumbar Spinal Stenosis

Percutaneous Endoscopic Unilateral-Approach Bilateral Decompression for Lumbar Spinal Stenosis

Published on: February 9, 2024

The Third Channel-Assisted Unilateral Biportal Endoscopic Technique for Lumbar Spinal Stenosis Combined with Contralateral Disc Herniation

The Third Channel-Assisted Unilateral Biportal Endoscopic Technique for Lumbar Spinal Stenosis Combined with Contralateral Disc Herniation

Published on: November 17, 2023

Full-Endoscopic Interlaminar Approach for Decompression of Lateral Recess Stenosis

Full-Endoscopic Interlaminar Approach for Decompression of Lateral Recess Stenosis

Published on: February 24, 2023

Area of Science:

Orthopedics
Neurosurgery
Geriatrics

Background:

Lumbar spinal stenosis (LSS) is primarily caused by degenerative changes, increasingly diagnosed in aging populations.
Improved diagnostic imaging contributes to higher LSS diagnosis rates.
LSS presents a spectrum from asymptomatic to severe disability, necessitating careful clinical evaluation.

Purpose of the Study:

To review current knowledge on LSS pathophysiology, diagnosis, and management, focusing on radicular symptoms.
To update understanding of degenerative central and lateral stenosis.
To evaluate treatment options for LSS.

Main Methods:

Literature review focusing on LSS pathophysiology, diagnosis, and management.
Analysis of studies concerning degenerative central and lateral stenosis.
Assessment of evidence for commonly used LSS treatments.

Main Results:

Clinical diagnosis relies on symptoms and examination, with imaging aiding decisions for invasive treatments.
Limited high-quality data exists on the comparative effectiveness of LSS treatments.
A lack of consensus on LSS definition complicates research interpretation.

Conclusions:

Evidence supports decompressive laminectomy for persistent, bothersome LSS symptoms.
A shared decision-making approach is recommended due to treatment trade-offs and patient variability.
Further research is needed to clarify optimal LSS management strategies.