Related Experiment Video
Updated: Jun 15, 2026
09:15
Vinyl Chloride and High-Fat Diet as a Model of Environment and Obesity Interaction
Published on: January 12, 2020
Eating when empty is good for your health.
David Lovell-Smith1, Timothy Kenealy, Stephen Buetow
1Hillmorton Medical Centre, 21 Coppell Place, Christchurch, New Zealand. davidlovell-smith@clear.net.nz
Medical Hypotheses
|March 16, 2010
Summary
Eating is regulated by pleasure when hunger is felt as an Empty Hollow Sensation (EHS). The Empty Hollow Sensation Meal Pattern (EHSMP) may help prevent overeating and related health issues.
Area of Science:
- Physiology
- Behavioral Science
- Public Health
Background:
- Poorly regulated eating contributes to obesity, diabetes, and heart disease.
- Misinterpreted hunger signals can lead to non-regulated eating patterns.
- Existing eating models do not adequately address the role of true hunger cues.
Purpose of the Study:
- To propose the Empty Hollow Sensation Meal Pattern (EHSMP) as a method for regulated eating.
- To investigate the role of eating pleasure in regulating food intake.
- To review evidence supporting the efficacy of EHSMP.
Main Methods:
- Review of existing scientific literature on eating regulation and hunger.
- Hypothetical framework linking eating pleasure, desire to eat, and Empty Hollow Sensation (EHS).
- Proposal of the EHSMP regime.
Main Results:
- Eating pleasure is hypothesized to extinguish the desire to eat when it fulfills the EHS.
- Maximized eating pleasure occurs when eating is prompted by EHS.
- Absent or misinterpreted hunger signals are linked to non-regulated eating.
Conclusions:
- The EHSMP, characterized by the presence of EHS before meals, is suggested for regulated eating.
- The EHSMP has the potential to aid in preventing and treating conditions linked to overeating.
- Further evidence review supports the potential efficacy of the EHSMP for well-being.
Related Concept Videos
01:06Lipid Digestion
Lipids are large molecules that are generally not water-soluble. Since most of the digestive enzymes in the human body are water-based, there are specific steps the body must take to break down lipids and make them available for use.
01:31Lipid-derived Compounds in the Human Body
Fats and lipids are crucial components in the human body. Some lipid-derived compounds, such as fat-soluble vitamins, eicosanoids, lipoproteins, and glycolipids, also play unique roles to support various biological processes .
Fat-soluble Vitamins
Fat-soluble vitamins, including vitamins A, D, E, and K, are required in minimal quantities, but their deficiencies can lead to severely abnormal physiological conditions. For example, vitamin A deficiency can cause night blindness, dry skin, delayed...
Fat-soluble Vitamins
Fat-soluble vitamins, including vitamins A, D, E, and K, are required in minimal quantities, but their deficiencies can lead to severely abnormal physiological conditions. For example, vitamin A deficiency can cause night blindness, dry skin, delayed...
01:06Fats as Energy Storage Molecules
Triglycerides are a form of long-term energy storage molecules. They are made of glycerol and three fatty acids. To obtain energy from fat, triglycerides must first be broken down by hydrolysis into their two principal components, fatty acids and glycerol. This process, called lipolysis, takes place in the cytoplasm. The resulting fatty acids are oxidized by β-oxidation into acetyl-CoA, which is used by the Krebs cycle. The glycerol that is released from triglycerides after lipolysis directly...
01:06Fats as Energy Storage Molecules
Triglycerides are a form of long-term energy storage molecules. They are made of glycerol and three fatty acids. To obtain energy from fat, triglycerides must first be broken down by hydrolysis into their two principal components, fatty acids and glycerol. This process, called lipolysis, takes place in the cytoplasm. The resulting fatty acids are oxidized by β-oxidation into acetyl-CoA, which is used by the Krebs cycle. The glycerol that is released from triglycerides after lipolysis directly...
01:24Peroxisomes
Peroxisomes are specialized organelles present in fungi, plant, and animal cells. It can vary in number, size, morphology, and activity depending on the type of tissue and the nutritional state of the cell. For example, cells with active lipid metabolism, such as adipocytes, neurons, and hepatocytes, have more peroxisomes than other cells in the body. Besides their primary role in breaking down complex organic molecules, peroxisomes can also synthesize specific macromolecules and participate in...
02:39Nomenclature of Alkynes
Alkynes are unsaturated hydrocarbons characterized by the presence of carbon-carbon triple bonds and have a general formula CnH2n-2. The nomenclature of alkynes follows a set of rules similar to alkanes and alkenes; however, alkynes bear the suffix "-yne" instead of "-ane" or "-ene." There are two approaches to naming alkynes: