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Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children
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Published on: August 22, 2012

Infantile hookworm disease.

Vidyut Bhatia1, Manoja Kumar Das, Pawan Kumar

  • 1Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India.

Indian Pediatrics
|March 16, 2010
PubMed
Summary
This summary is machine-generated.

Hookworm infection in infants is rare but can cause severe symptoms like anemia and poor weight gain. Diagnosis often requires endoscopy when initial stool tests are inconclusive.

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Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Gastroenterology

Background:

  • Hookworm infection is a widespread parasitic disease, primarily affecting children in tropical and subtropical regions.
  • While common in older children, hookworm infestation in neonates and infants is exceptionally rare and underreported.

Observation:

  • Two cases of hookworm infestation in infants are presented.
  • Infants exhibited severe clinical signs including malena (dark, tarry stools), profound pallor, lethargy, and failure to thrive.
  • Initial stool examinations failed to detect hookworm ova or parasites.

Findings:

  • Diagnosis was definitively established through upper gastrointestinal endoscopy.
  • Endoscopic visualization confirmed hookworm presence in the upper gastrointestinal tract.

Implications:

  • This case series highlights the importance of considering hookworm infection in infants presenting with severe gastrointestinal bleeding and anemia, even with negative initial stool results.
  • Upper gastrointestinal endoscopy is a crucial diagnostic tool for hookworm infestation in neonates and infants when standard methods are insufficient.
  • Early diagnosis and treatment are vital to prevent severe complications and ensure proper growth and development in affected infants.