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Updated: Jun 15, 2026

Mass Spectrometry-Guided Genome Mining as a Tool to Uncover Novel Natural Products
Published on: March 12, 2020
Exploratory research on bioactive natural products with a focus on biological phenomena
1Department of Biosciences and Informatics, Faculty of Science and Technology, Keio University, Kanagawa, Japan. uemura@bio.keio.ac.jp
Abstract:
The discovery of new basic compounds holds the key for advancing material sciences. We have focused on the identification and characterization of natural key compounds that control biologically and physiologically intriguing phenomena. The discovery of new bioactive molecules, facilitated by a deeper understanding of nature, should advance our knowledge of biological processes and lead to new strategies to treat disease. The structure and function of natural compounds are sometimes unexpectedly original. Based on our past experience and results, we have carried out research to find new directions for compound exploration by directly learning from dynamic biological phenomena in the field, and have succeeded in creating a new research field in biological molecular sciences.
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