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Updated: Jun 15, 2026

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion
Published on: May 26, 2022
[Treatment of hypertension in diabetic patients]
1Präsident der Osterreichischen Gesellschaft für Hypertensiologie, Wien, Osterreich. joerg@slany.org
Insights
Effective hypertension management is crucial for patients with diabetes and visceral adiposity to prevent cardiovascular and renal complications. Achieving strict blood pressure control, often with combination therapy and lifestyle changes, is essential.
Area of Science:
- Cardiology
- Endocrinology
- Nephrology
Context:
- Hypertension, diabetes, and visceral adiposity frequently coexist.
- These comorbidities significantly elevate the risk of cardiovascular and renal complications.
Purpose:
- To outline essential treatment strategies for managing hypertension in patients with diabetes and visceral adiposity.
- To emphasize the importance of achieving strict blood pressure control.
Summary:
- Recommended blood pressure goal: below 130/80 mmHg (office) and <7/30 values <135/85 mmHg (home).
- Treatment typically requires combination therapy, starting with RAS inhibitors plus calcium channel blockers and/or diuretics.
- Fixed-dose combinations and newer beta-blockers can be utilized. Lifestyle modifications are critical.
Impact:
- Strict blood pressure control demonstrably reduces macro- and microvascular morbidity.
- Comprehensive management is necessary to mitigate severe health outcomes associated with these conditions.
Abstract:
Hypertension, diabetes and visceral adiposity are very common co-morbidities with an exceedingly high risk of cardiovascular and renal complications. Therefore, emphatic treatment is necessary. Blood pressure goal is recommended below 130/80 mmHg with office measurements, and less than 7 out of 30 values below 135/85 mmHg with home measurements. Strict blood pressure control reduces macro- and microvascular morbidity. Usually combination of different drugs is necessary to achieve a satisfactory blood pressure control. First line should be an inhibitor of the RAS, commonly combined with a calcium channel blocker and/or a diuretic. Fixed-dose combinations are recommended. If indicated or necessary, newer generation betablockers may be given as an adjunct. Life style measures and active reduction of further risk factors are essential.
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