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Updated: Jun 15, 2026
05:33
Three-Dimensional Shape Modeling and Analysis of Brain Structures
Published on: November 14, 2019
On two equations about brain volume, cranial capacity and age
Anne-Sophie Ricard1, Pascal Desbarats, Mathieu Laurentjoye
1Service de Chirurgie Maxillofaciale, Centre Hospitalier Universitaire Pellegrin, Place Amélie Raba Léon, 33076, Bordeaux, France. annericard@aol.com
Surgical and Radiologic Anatomy : SRA
|March 16, 2010
Summary
Brain volume in healthy adults is closely related to cranial capacity. Age also influences this relationship, with brain volume decreasing slightly as individuals get older.
Area of Science:
- Neuroimaging
- Human Anatomy
Background:
- Cranial capacity and brain volume are key metrics in neuroscience.
- Understanding their relationship with age is crucial for healthy aging research.
Purpose of the Study:
- To investigate the correlation between brain volume and cranial capacity in healthy adults.
- To determine the influence of age on brain volume and cranial capacity.
Main Methods:
- Utilized computed tomography (CT) imaging protocols.
- Examined 58 healthy adult volunteers (27 women, 31 men) aged 18-95.
- Excluded individuals with a history of neuropsychiatric illness or substance abuse.
Main Results:
- Mean intracranial volume was 1,384.6 cm³ (SD=135.27).
- Mean brain volume was 1,201.0 cm³ (SD=142.52).
- Established regression formulas: brain volume = 182.3 + 0.7 × cranial capacity; and brain volume = 396.5 - 3.5 × age + 0.7 × cranial capacity.
Conclusions:
- Brain volume is significantly correlated with cranial capacity.
- Age has a discernible, albeit smaller, impact on brain volume.
- Further research on brain size and stature is recommended.
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