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Visualization of interaction between ribosome-inactivating proteins and supercoiled DNA with an atomic force

X Wu1, W Liu, Z Ouyang

  • 1Shanghai Institute of Biochemistry, Chinese Academy of Sciences, 200031, Shanghai, China.

Science in China. Series C, Life Sciences
|March 16, 2010
PubMed

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Atomic Force Microscopy

Atomic force microscopy (AFM) is a type of scanning probe microscopy that can analyze topographic details of various specimens like ceramics, glass, polymers, and biological samples. AFM offers over 1000 times more resolution than the optical imaging system. Images generated from AFM are three-dimensional surface profiles, offering an advantage over the flat, two-dimensional images from other imaging techniques.
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The probe is regarded as the heart of any AFM setup and comprises the...