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N,N'-methylenediimidazolium salts: from self-assembly to an efficient DNAse protection system
Christophe Pardin1, Loïc Leclercq, Andreea R Schmitzer
1Department of Chemistry, Université de Montréal, C.P. 6128 Succursale Centre-ville, Montréal, Québec, H3C 3J7 (Canada), Fax: (+1) 514-343-7586.
Chemistry (Weinheim an Der Bergstrasse, Germany)
|March 16, 2010
Abstract:
We have developed N,N'-dialkylmethylenediimidazolium salts ([C(n)C(n)DIM][X]2) that self-organize into multilayered cationic vesicles and can interact with DNA. These preorganized systems form complexes with linear DNA and protect it from DNase I cleavage.
