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Related Experiment Video

Updated: Jun 15, 2026

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation
08:43

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation

Published on: May 31, 2016

[Madelung's disease].

Dariusz Waniczek1, Krzysztof Buda, Wojciech Mikusek

  • 1Katedra i Oddział Kliniczny Chirurgii Ogólnej i Gastroenterologicznej Wydziału Lekarskiego z Oddziałem Lekarsko-Dentystycznym SUM, Szpital Specjalistyczny Nr 1 w Bytomiu.

Wiadomosci Lekarskie (Warsaw, Poland : 1960)
|March 17, 2010
PubMed
Summary
This summary is machine-generated.

Madelung's disease (Md) involves fatty neck masses. Surgical removal can effectively treat symptoms and improve appearance, with no recurrence observed in a three-year study.

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Last Updated: Jun 15, 2026

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation
08:43

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation

Published on: May 31, 2016

Area of Science:

  • Metabolic Disorders
  • Surgical Oncology
  • Plastic Surgery

Background:

  • Madelung's disease (Md) is a rare metabolic disorder characterized by symmetrical fatty masses, primarily affecting the head, neck, and nape.
  • Indications for treatment include respiratory distress, restricted head movement, dysphagia, aesthetic concerns, and cancer-related anxiety.
  • Standard treatment involves surgical excision of pathological adipose tissue.

Observation:

  • The authors present a three-year observational case study of a patient with Madelung's disease who underwent surgical treatment.
  • The observation focused on the outcomes of surgical intervention for the characteristic fatty masses.

Findings:

  • Surgical excision resulted in significant symptom subsidence, including improvements in breathing and swallowing.
  • Aesthetically pleasing results were achieved post-surgery.
  • No signs of disease recurrence were noted during the three-year follow-up period.

Implications:

  • Surgical intervention appears to be an effective treatment for Madelung's disease, offering both functional and cosmetic benefits.
  • Long-term follow-up suggests that surgical management can potentially prevent disease relapse.
  • This case study supports the role of surgical excision in managing Madelung's disease and warrants further investigation into long-term outcomes.