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Two Methods of Heterokaryon Formation to Discover HCV Restriction Factors
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[Co-infection of HIV with HCV and HBV]

Kazuhiko Koike1

  • 1Department of Gastroenterology, Graduate School of Medicine, University of Tokyo.

Nihon Rinsho. Japanese Journal of Clinical Medicine
|March 17, 2010
PubMed

Since the dissemination of HAART, the morbidity and mortality associated with HIV infection have declined. However, the reduction in mortality due to opportunistic infection has made HCV-associated liver diseases the leading cause of mortality in Western countries. We conducted a nationwide survey to determine the prevalence of coinfection with HIV and HCV by distributing a questionnaire to the hospitals in HIV/AIDS Network of Japan. Nineteen point two percent were also positive for the anti-HCV antibody. Most (84.1%) of the patients coinfected with HIV and HCV were recipients of blood products. Six point three percent were positive for HBs antigen, and had ongoing HBV infection.

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