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Related Experiment Video

Updated: Jun 15, 2026

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Published on: December 15, 2011

The generalized rash: part II. Diagnostic approach.

John W Ely¹, Mary Seabury Stone

¹University of Iowa Carver College of Medicine, 200 Hawkins Dr., Iowa City, IA 52242, USA. john-ely@uiowa.edu

American Family Physician

|March 17, 2010

Summary

Diagnosing generalized rashes involves a broad differential diagnosis, narrowed by focused history and key clinical features. This guide details common, uncommon, and rare causes and their distinguishing characteristics.

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A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma

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Published on: June 4, 2017

Area of Science:

Dermatology
Internal Medicine

Background:

Generalized rashes present a diagnostic challenge requiring a systematic approach.
An inclusive differential diagnosis is essential initially.

Purpose of the Study:

To outline common, uncommon, and rare causes of generalized rashes.
To describe key clinical features aiding in the differentiation of these rashes.

Main Methods:

Review of common, uncommon, and rare causes of generalized rashes.
Description of distinguishing clinical features, including history, lesion characteristics, distribution, and associated symptoms.

Main Results:

Part I lists various etiologies of generalized rashes.
Part II details specific historical elements and physical examination findings crucial for diagnosis.

Conclusions:

A focused history and identification of key clinical features are vital for narrowing the differential diagnosis of generalized rashes.
Understanding lesion characteristics, distribution, and systemic signs aids in accurate diagnosis.