Leech therapy in cutaneous surgery and disease
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Updated: Jun 15, 2026

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Published on: February 10, 2021
Adam J Mamelak1, Adrianna Jackson, Rabia Nizamani
1Department of Dermatology, The Methodist Hospital, Houston, TX , USA. amamelak@gmail.com
Background:
Over the ages, the use of leeches in medicine has evolved from haphazard bloodletting to a well-understood physiologic process with defined, rational applications.
Objective:
The authors describe the current role of leech therapy in cutaneous surgery and medicine.
Methods:
Case series and review of the literature.
Results:
Leech saliva contains anticoagulative, anti-aggregative and vasodilatory components. Combined with the annelid's mechanical ability to extract blood, leeches can contribute to patients' health with minimal risks.
Conclusion:
Leeches should be considered as novel therapies for disorders of coagulation and venous congestion. Implementation of leech treatment should be tempered with the potential adverse effects, including Aeromonas infection and a drop in hematocrit that might require a blood transfusion.
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