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Published on: January 9, 2026
In the beginning there was colectomy: current surgical options in familial adenomatous polyposis
Daniel R McGrath1, Allan D Spigelman
1Discipline of Surgical Science, University of Newcastle, Australia. allan.spigelman@newcastle.edu.au.
Abstract:
Multiple colonic polyps, almost guaranteed colorectal cancer by the age of forty-five and an increased risk of non-colonic cancers characterise the autosomal dominant condition Familial Adenomatous Polyposis (FAP) 1. The patients and families faced with such a diagnosis present many difficult management challenges, both surgical and non-surgical. We discuss the current surgical options for treatment of the more significant manifestations of FAP arising in the colorectum and duodenum as well as desmoid disease.
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