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Related Experiment Video

Updated: Jun 15, 2026

Visualizing Non-lytic Exocytosis of Cryptococcus neoformans from Macrophages Using Digital Light Microscopy

Visualizing Non-lytic Exocytosis of Cryptococcus neoformans from Macrophages Using Digital Light Microscopy

Published on: October 21, 2014

Explosive nasofacial cryptococosis.

Paul Persad¹, Rajendrakumar Patel, Jeffery Stephens

¹Mercer University School of Medicine, Macon, Georgia, USA. paulpersad@yahoo.com

Dermatology Online Journal

|March 18, 2010

Summary

This summary is machine-generated.

Cryptococcal infections can affect the skin, particularly in individuals with acquired immunodeficiency syndrome (AIDS). This case highlights a rare nasal and facial cryptococcal infection following a traumatic acid injury.

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Area of Science:

Mycology
Infectious Diseases
Dermatology

Background:

Cryptococcal skin infections are recognized in immunocompromised individuals, notably those with acquired immunodeficiency syndrome (AIDS).
The typical presentation and common sites of cutaneous cryptococcosis are well-documented.

Observation:

A patient presented with a severe nasal and facial infection.
The infection occurred subsequent to a traumatic injury involving battery acid exposure.

Findings:

The patient was diagnosed with a cryptococcal infection affecting the facial and nasal regions.
This represents an unusual manifestation of cryptococcosis, potentially linked to the specific injury mechanism.

Implications:

This case expands the understanding of potential routes for cryptococcal inoculation and infection.
It underscores the importance of considering fungal infections in unusual presentations following trauma, especially in susceptible populations.
Further investigation into the interaction between chemical injury and fungal pathogenesis may be warranted.