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[Letter: Tinea faciei exacerbated by topical immunomodulation: Two case reports]

Ricardo Ruiz-Villaverde, Daniel Sanchez-Cano

    Dermatology Online Journal
    |March 18, 2010
    PubMed

    Insights

    Topical pimecrolimus cream can worsen fungal infections of the face (tinea faciei) in children. This highlights another medication that can exacerbate dermatophyte infections, similar to topical corticosteroids.

    Area of Science:

    • Dermatology
    • Mycology
    • Pediatrics

    Background:

    • Tinea faciei, a fungal infection of the face, is often categorized under tinea corporis.
    • Understanding the clinical presentation and management of tinea faciei is crucial in pediatric dermatology.

    Observation:

    • Two pediatric cases of tinea faciei were evaluated.
    • Both cases showed disease exacerbation following topical application of pimecrolimus cream.

    Findings:

    • Topical pimecrolimus cream demonstrated an exacerbating effect on tinea faciei.
    • This finding adds to the known adverse effects of immunosuppressants on dermatophyte infections.

    Implications:

    • Pimecrolimus cream should be used with caution in patients with suspected or confirmed fungal facial infections.
    • Clinicians should be aware of pimecrolimus's potential to worsen dermatophyte infections, alongside topical corticosteroids.

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