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Spread of ropivacaine by a weight-based formula in a pediatric caudal block: a fluoroscopic examination
1Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Korea.
Insights
Weight-based doses of ropivacaine provide effective caudal blocks for pediatric infra-umbilical surgery. This study confirms these doses cover the necessary spinal segments, with younger children experiencing wider drug spread.
Area of Science:
- Pediatric Anesthesiology
- Regional Anesthesia
- Pharmacology
Background:
- Caudal block is a primary method for post-operative pain relief in pediatric infra-umbilical surgery.
- Determining the extent of spinal coverage with weight-based ropivacaine doses is crucial for effective analgesia.
- Fluoroscopic guidance aids in visualizing drug distribution within the extradural space.
Purpose of the Study:
- To ascertain the spinal segment coverage achieved by weight-based doses of 0.2% ropivacaine administered caudally in children.
- To evaluate the efficacy of ropivacaine for pediatric caudal blocks using fluoroscopic imaging.
Main Methods:
- A study involving 83 ASA I boys undergoing day-case urological surgery.
- Three dosage groups were established based on surgical site: 0.5 ml/kg (perineal), 1 ml/kg (inguinal hernia), and 1.25 ml/kg (orchiopexy).
- Ropivacaine mixed with radiopaque dye was injected caudally, and its spread was immediately assessed via fluoroscopy.
Main Results:
- The highest spinal levels reached were L2 (L4-T12) for 0.5 ml/kg, T12 (L1-T8) for 1 ml/kg, and T10 (L2-T7) for 1.25 ml/kg.
- A statistically significant wider spread of the anesthetic was observed in younger children (infants and toddlers) compared to older children.
- Fluoroscopic examination confirmed the extradural spread of ropivacaine in relation to injected volumes.
Conclusions:
- The weight-based dosages of ropivacaine, similar to those previously suggested for bupivacaine, effectively cover the required spinal levels for various pediatric infra-umbilical surgeries.
- Fluoroscopic findings support the use of established weight-based caudal ropivacaine doses for targeted surgical anesthesia in children.
- Age is a factor influencing the spread of caudal ropivacaine, with younger patients demonstrating greater cephalad distribution.
Background:
Caudal block is the most common regional technique to provide post-operative analgesia in pediatric infra-umbilical surgery. This study was designed to define how many spinal segments would be covered by the weight-based dosage of caudally administered 0.2% ropivacaine in children using the fluoroscopic method.
Methods:
After an approval from the institutional human research review board, in 83 ASA I boys undergoing day-case urological surgery, the distribution of ropivacaine mixed with a radioactive dye in relation to the volume injected caudally was studied. Three groups were studied: for perineal surgery 0.5 ml/kg (group C(0.5)), for inguinal hernia repair 1 ml/kg (group C(1.0)), and for orchiopexy 1.25 ml/kg (group C(1.25)). The dose of 0.2% ropivacaine containing radiopaque dye at a ratio of 1 : 4 was injected at a rate of 1 ml 3 s(-1). Fluoroscopic examination was performed immediately to define the level of the drug spread within the extradural space.
Results:
The highest spinal levels [median with ranges] of spread were L2 [L4-T12] in group C(0.5), T12 [L1-T8] in group C(1.0), and T10 [L2-T7] in group C(1.25). Analysis by age distribution (infants: <12 months; toddlers: 12-36 months; and children: >36 months) revealed a larger spread in younger patients.
Conclusions:
Based on the fluoroscopic findings, the weight-based doses for caudally administered 0.2% bupivacaine suggested by Armitage are also useful for ropivacaine to block the spinal level required for the different types of surgeries studied.
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