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Diagnostic accuracy of features predicting lower gastrointestinal malignancy: a colonoscopy database review of 10,603
1Department of Gastroenterology, Changhai Hospital, Second Military Medical University, Shanghai, China Center for Clinical Epidemiology & Evidence-Based Medicine, Second Military Medical University, Shanghai, China.
Aim:
The diagnostic accuracy of colonoscopic features in predicting colorectal cancer (CRC) malignancy was studied.
Method:
Consecutive patients who underwent first-time colonoscopy for lower gastrointestinal (GI) symptoms from 1998 to 2009 were identified. Gender, age, symptoms, endoscopic and pathologic findings were reviewed.
Results:
There were 10,603 patients. The overall prevalence of malignancy was 3.0% (313). Among these, only 58% (181/313) had features indicative of tumour formation. The overall sensitivity and specificity was 9.6% and 94.1%, respectively. The overall positive likelihood ratio, negative likelihood ratio and diagnostic odds ratio were 2.66, 0.96 and 2.77, respectively.
Conclusion:
A large proportion of Chinese patients with CRC presented without features indicative of tumour formation.
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