Neonatal seizures

The clinician caring for newborn infants must be aware of the clinical implications of a seizure in a neonate. The diagnostic possibilities are many including generalized, systemic conditions in addition to central nervous system problems. It is important for the clinicians to be able to distinguish nonepileptic abnormal neurologic findings from seizures requiring anticonvulsant therapy. The decision to treat with anticonvulsants must be based on a comprehensive evaluation of the infant excluding secondary, self-limiting courses of seizures. Anti-convulsant therapy is a significant commitment so the clinician must be familiar with the drugs to be used.