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Transport Number

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The transport number is the fraction of the total current carried by an ion in an electrolyte solution. It is defined as the ratio of the current carried by a specific ion to the total current flowing through the solution. The transport number, t, is central to understanding ionic mobility, which describes how fast an ion moves under the influence of an electric field. This link connects the physical behavior of ions in solution to the chemical processes that occur during electrochemical...

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Related Experiment Video

Updated: Jun 15, 2026

Single-Molecule Imaging of Lateral Mobility and Ion Channel Activity in Lipid Bilayers using Total Internal Reflection Fluorescence (TIRF) Microscopy

Single-Molecule Imaging of Lateral Mobility and Ion Channel Activity in Lipid Bilayers using Total Internal Reflection Fluorescence (TIRF) Microscopy

Published on: February 17, 2023

Lorentz effect imaging of ionic currents in solution using correct values for ion mobility.

Ranjith S Wijesinghe¹, Bradley J Roth

¹Department of Physics and Astronomy, Ball State University, Muncie, IN 47306, USA. rswijesinghe@bsu.edu

Journal of Magnetic Resonance (San Diego, Calif. : 1997)

|March 19, 2010

Summary

This summary is machine-generated.

Lorentz effect imaging (LEI) was proposed to detect ionic currents. However, using accurate ion mobility values shows LEI cannot directly image neural currents using magnetic resonance imaging.

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Area of Science:

Biophysics
Neuroimaging
Electrophysiology

Background:

Lorentz effect imaging (LEI) was recently introduced as a novel method to detect ionic currents in solutions.
The primary objective was to leverage the Lorentz force on ions within a static magnetic field as a contrast mechanism for magnetic resonance imaging (MRI) of neural currents.

Purpose of the Study:

To re-evaluate the feasibility of Lorentz effect imaging (LEI) for neural current detection.
To determine if LEI can serve as a contrast mechanism in magnetic resonance imaging (MRI) for neural activity.

Main Methods:

Utilized corrected ion mobility values in the analysis.
Performed theoretical investigations and simulations based on established biophysical principles.
Compared findings with previous studies that employed incorrect ion mobility data.

Main Results:

The application of accurate ion mobility values significantly alters the predicted signal response.
Calculations demonstrate that the Lorentz force effects are insufficient for direct neural current imaging with MRI.
Previous findings suggesting LEI's utility for neural currents were based on erroneous mobility data.

Conclusions:

Lorentz effect imaging (LEI) is not a viable method for the direct imaging of neural currents using MRI.
The accurate biophysical parameters, specifically ion mobilities, are critical for the validity of imaging techniques.
Further research into alternative MRI contrast mechanisms for neural activity is warranted.