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Related Experiment Videos

Reliability of visual field results over repeated testing.

J Katz1, A Sommer, K Witt

  • 1Dana Center for Preventive Ophthalmology, Wilmer Institute, Johns Hopkins Medical Institutions, Baltimore 21205.

Ophthalmology
|January 1, 1991
PubMed
Summary

Visual field testing reliability in glaucoma patients showed no trends over time. Repeated unreliability was mainly due to fixation losses, not glaucoma progression.

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Area of Science:

  • Ophthalmology
  • Neuroscience
  • Medical Technology

Background:

  • Visual field testing is crucial for diagnosing and monitoring glaucoma.
  • Assessing the long-term reliability of visual field test results is essential for accurate patient management.
  • The Humphrey Field Analyzer (HFA) is a standard device for visual field testing.

Purpose of the Study:

  • To evaluate the long-term reliability of visual field testing in normal subjects, ocular hypertension, and glaucoma patients.
  • To determine if specific reliability indices change over time.
  • To differentiate between patient reliability issues and disease-specific test abnormalities.

Main Methods:

  • Longitudinal study over 6 years with at least three C-30-2 tests on the Humphrey Field Analyzer.

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  • Inclusion of 51 normal subjects, 337 with ocular hypertension, and 55 glaucoma patients.
  • Application of manufacturer's reliability standards (false-positive/negative rates <33%, fixation losses <20%).

    • Main Results:

    • No significant trends in the proportion of reliable visual fields or component indices were observed over a 6-year period.
    • A small percentage of subjects (4-9%) repeatedly failed to meet reliability standards, primarily due to fixation losses.
    • Glaucoma patients showed a higher likelihood of repeatedly high false-negative responses compared to normal subjects and ocular hypertension patients.

    Conclusions:

    • Long-term visual field testing demonstrates consistent reliability in normal subjects, ocular hypertension, and glaucoma patients.
    • Repeated unreliability in visual field testing is predominantly linked to fixation issues, not disease progression.
    • High false-negative rates in glaucoma patients may indicate disease severity rather than poor test reliability.