Related Experiment Video
Updated: Jun 15, 2026

Isolation of Cells with Morphological and Spatial Information from Oral Submucous Fibrosis Samples by Laser Capture Microdissection
Published on: August 11, 2023
Elastofibromatous changes and hyperelastosis of the oral mucosa
Konstantinos I Tosios1, Ioanna Economou, Nektarios-Nikolaos Vasilopoulos
1Department of Oral Pathology and Surgery, School of Dentistry, National and Kapodestrian University of Athens, Athens, Greece.
Abstract:
Three cases of abnormalities of elastic fibers, two of them on the floor of the mouth and one on the lingual alveolar mucosa, close to the floor of the mouth, in a patient with history of homolateral squamous cell carcinoma of the floor of the mouth, are presented. Comparison with elastofibromatous changes and elastofibromas are made and their possible pathogenesis is discussed. It is suggested that increased awareness may facilitate recognition of such lesions as they can be easily overlooked, especially when they do not present as discrete tumors or they are associated with other "more significant" pathologic processes.
Related Concept Videos
Elastin is Responsible for Tissue Elasticity
Ligaments and tendons are made of dense regular connective tissue, but in ligaments not all fibers are parallel. Dense regular elastic tissue contains elastin fibers and...
Chronic Inflammation: Introduction
Cellular Adaptation IV: Dysplasia and Metaplasia
Assessment of the Mouth
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
Cirrhosis I: Introduction
Extracellular Matrix
