Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Inflammatory Bowel Disease I: Introduction01:26

Inflammatory Bowel Disease I: Introduction

Inflammatory bowel disease is a group of chronic disorders marked by recurrent inflammation of the gastrointestinal tract due to an abnormal immune response against gut microflora. This leads to tissue damage. The two main forms are Crohn’s disease and ulcerative colitis.Crohn’s DiseaseCrohn’s disease is a relapsing inflammatory disorder that can affect any part of the GI tract, from the mouth to the anus. It involves all layers of the bowel wall (transmural) and shows “skip lesions” in which...
Inflammatory Bowel Disease II: Ulcerative Colitis01:20

Inflammatory Bowel Disease II: Ulcerative Colitis

Ulcerative colitis is a chronic inflammatory disorder of the colon characterized by continuous mucosal inflammation that typically begins in the rectum and extends proximally in a uniform pattern. Its pathogenesis involves a complex interplay of genetic predisposition, immune dysregulation, and environmental influences. These factors converge to impair the colon’s epithelial defenses and promote an exaggerated inflammatory response against luminal contents.Breakdown of the Mucosal BarrierA...
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory Bowel Disease IV: Clinical Manifestations01:20

Inflammatory Bowel Disease IV: Clinical Manifestations

Inflammatory bowel disease (IBD) encompasses two major chronic disorders—ulcerative colitis and Crohn’s disease—each characterized by relapsing episodes of gastrointestinal inflammation. Although they share certain clinical features, their patterns of involvement and manifestations differ in ways that aid diagnosis and guide management.Ulcerative ColitisUlcerative colitis is limited to the colon and rectum and involves continuous inflammation of the mucosal layer. The disease course is marked...
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

ON ULCERATING GRANULOMA OF THE PUDENDA: SYNONYMS. GRANULOMA VENEREUM. GRANULOMA INGUINALE.

The British journal of venereal diseases·2011
Same author

Correspondence.

Postgraduate medical journal·2011
Same author

The Jubilee of Sir Patrick Manson (1878-1938): A Tribute to his Work on the Malaria Problem.

Postgraduate medical journal·2011
Same author

Some tropical diseases in general practice; a post-war legacy.

Glasgow medical journal·2010
Same author

Tropical medicine in the British Empire.

Nature·2010
Same author

Effects of tropical diseases on the ex-service man.

Nursing times·2010
Same journal

EDISWAN Mark II electro-encephalograph.

The overseas post-graduate medical journal·2014
Same journal

Simmonds' disease.

The overseas post-graduate medical journal·2014
Same journal

The relief of pain.

The overseas post-graduate medical journal·2014
Same journal

The pathogenesis and treatment of the megaloblastic anaemias.

The overseas post-graduate medical journal·2014
Same journal

Cirrhosis of the liver.

The overseas post-graduate medical journal·2014
Same journal

Diet and the milk drip.

The overseas post-graduate medical journal·2014
See all related articles

Related Experiment Video

Updated: Jun 15, 2026

Investigating Intestinal Inflammation in DSS-induced Model of IBD
08:43

Investigating Intestinal Inflammation in DSS-induced Model of IBD

Published on: February 1, 2012

Dysentery and colitis

P MANSON-BAHR

    The Overseas Post-Graduate Medical Journal
    |March 19, 2010
    PubMed
    Summary

    No abstract available in PubMed .

    Keywords:
    COLITIS/therapyDYSENTERY

    More Related Videos

    Murine Colitis Modeling using Dextran Sulfate Sodium (DSS)
    08:39

    Murine Colitis Modeling using Dextran Sulfate Sodium (DSS)

    Published on: January 19, 2010

    Injections of Lipopolysaccharide into Mice to Mimic Entrance of Microbial-derived Products After Intestinal Barrier Breach
    08:24

    Injections of Lipopolysaccharide into Mice to Mimic Entrance of Microbial-derived Products After Intestinal Barrier Breach

    Published on: May 2, 2018

    Related Experiment Videos

    Last Updated: Jun 15, 2026

    Investigating Intestinal Inflammation in DSS-induced Model of IBD
    08:43

    Investigating Intestinal Inflammation in DSS-induced Model of IBD

    Published on: February 1, 2012

    Murine Colitis Modeling using Dextran Sulfate Sodium (DSS)
    08:39

    Murine Colitis Modeling using Dextran Sulfate Sodium (DSS)

    Published on: January 19, 2010

    Injections of Lipopolysaccharide into Mice to Mimic Entrance of Microbial-derived Products After Intestinal Barrier Breach
    08:24

    Injections of Lipopolysaccharide into Mice to Mimic Entrance of Microbial-derived Products After Intestinal Barrier Breach

    Published on: May 2, 2018