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Updated: Aug 6, 2026

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Published on: August 20, 2007
[Celiac disease as a cause for occlusion of the small intestine]
1Pädiatrische Gastroenterologie, Regionales Krankenhaus, Bozen.
Insights
A 13-month-old boy experienced intestinal pseudo-obstruction, which resolved with parenteral nutrition. Despite villous atrophy on biopsy, he tolerated gluten, suggesting non-celiac causes for his intestinal issues.
Area of Science:
- Pediatric Gastroenterology
- Gastrointestinal Motility Disorders
- Enteropathies
Background:
- Intestinal pseudo-obstruction presents diagnostic challenges in infants.
- Differentiating functional and organic causes is crucial for appropriate management.
Observation:
- A 13-month-old boy exhibited symptoms and imaging consistent with paralytic intestinal occlusion.
- Intestinal motility normalized within 48 hours of initiating parenteral nutrition.
- Jejunal biopsy revealed total villous atrophy.
Findings:
- The patient's symptoms did not recur upon gluten challenge, ruling out celiac disease.
- The presentation shares similarities with obstructive events seen in cow's milk protein-sensitive enteropathy.
Implications:
- This case highlights the importance of considering non-celiac enteropathies in infantile intestinal pseudo-obstruction.
- Parenteral nutrition can be an effective initial treatment for motility restoration.
- Further investigation into cow's milk protein sensitivity may be warranted.
Abstract:
We report the case of a 13 month old boy presenting with an intestinal pseudo-obstruction. He showed the clinical and radiological features typical of a paralytic intestinal occlusion. After 48 hours of parenteral nutrition, the intestinal motility returned to normal. A jejunal biopsy showed total villous atrophy. The patient did not relapse with the same symptoms on a gluten challenge. The differential diagnosis and the similarities with obstructive events in cow's milk protein sensitive enteropathy are discussed.
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