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Post-myelographic meningeal irritation with iohexol
J Alexiou1, D Deloffre, J H Vandresse
1Department of Radiology, Clinique du Parc Léopold, Brussels, Belgium.
Neuroradiology
|January 1, 1991
Summary
A patient experienced meningeal irritation after iohexol myelography. Rapid improvement with antibiotics suggested chemical meningitis, not infection.
Area of Science:
- Neurology
- Radiology
- Pharmacology
Background:
- Myelography is an imaging procedure using contrast agents to visualize the spinal cord.
- Iohexol is a non-ionic, low-osmolar contrast medium commonly used in medical imaging.
- Meningeal irritation can be a complication following spinal procedures.
Observation:
- A 45-year-old woman presented with symptoms indicative of meningeal irritation post-myelography.
- The myelography procedure utilized the contrast agent iohexol.
- The patient received antibiotic treatment for her symptoms.
Findings:
- The patient exhibited rapid clinical improvement following antibiotic administration.
- Cerebrospinal fluid (CSF) analysis revealed pleocytosis and elevated protein levels.
- Pre-treatment CSF cultures were negative for pathogenic organisms.
- These findings collectively supported a diagnosis of chemical meningitis.
Implications:
- Chemical meningitis is a potential adverse reaction to iohexol contrast agents.
- Prompt diagnosis and treatment are crucial for favorable outcomes.
- Distinguishing chemical meningitis from infectious meningitis is important for appropriate management.
- This case highlights the need for vigilance regarding contrast-induced neurological complications.