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Late-onset globoid cell leukodystrophy mimicking an infiltrating glioma
M A Epstein1, R A Zimmerman, L B Rorke
1Department of Neurology, Children's Hospital, University of Pennsylvania School of Medicine, Philadelphia.
Pediatric Radiology
|January 1, 1991
Abstract:
A 3 1/2 year old girl who developed a gradual left hemiparesis and hemianopia is reported. Neuroimaging studies demonstrated an infiltrating-like high density lesion which crossed the splenium of the corpus callosum, thought to represent a glioma. Subsequent brain biopsy established the correct diagnosis of globoid cell leukodystrophy (GCL), which suggests that the radiographic appearance of late-onset GCL may mimic that of an infiltrating glioma.