Related Experiment Video
Updated: Jun 14, 2026

07:49
Measuring Local Anaphylaxis in Mice
Published on: October 14, 2014
Histamine and anaphylactic shock in the mouse
Summary
No abstract available in PubMed .
Related Concept Videos
Allergic Reactions
Overview
Allergic Reactions: Anaphylaxis
Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...

