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Heterogeneity of squamous cell carcinomas of the oral cavity studied by flow cytometry

M Tytor1, S Wingren, J Olofsson

  • 1Department of Otolaryngology, University Hospital, Linköping, Sweden.

Pathology, Research and Practice
|January 1, 1991
PubMed

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Flow Cytometry

The development of flow cytometry techniques began in 1934 with initial attempts by Andrew Moldavan, a bacteriologist who counted the cells in a flowing capillary system. Moldavan pumped cells through a capillary tube focused under a microscope for visualization. The invention of photometry allowed the measurement of differentially-stained cells, and Louis Kamentsky developed the first multiparameter flow cytometer in 1965 to identify and count the cancer cells in cervical tissue specimens.
In...