Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Serotonin, memory, and the aging brain.

W J McEntee1, T H Crook

  • 1Memory Assessment Clinics Inc., Sarasota, FL 34239.

Psychopharmacology
|January 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Neuropeptide dietary supplement N-PEP-12 enhances cognitive function and activates brain bioelectrical activity in healthy elderly subjects.

Methods and findings in experimental and clinical pharmacology·2005
Same author

Raloxifene hydrochloride, a selective estrogen receptor modulator: safety assessment of effects on cognitive function and mood in postmenopausal women.

Psychoneuroendocrinology·1999
Same author

Wernicke's encephalopathy: an excitotoxicity hypothesis.

Metabolic brain disease·1997
Same author

Nicergoline: parallel evolution of clinical trial methodology and drug development in dementias.

Dementia and geriatric cognitive disorders·1997
Same author

Age-associated memory impairment: sorting out the controversies.

Neurology·1995
Same author

Structure of everyday memory in adults with Age-Associated Memory Impairment.

Psychology and aging·1994
Same journal

Effects of repeated treatment with opioids that vary in mu opioid receptor efficacy on pain-depressed locomotor behavior in mice.

Psychopharmacology·2026
Same journal

Cannabidiol in the anterior insular cortex attenuates chronic neuropathic pain and comorbid anxiety- and depression-like behaviors: involvement of CB<sub>1</sub> and 5-HT<sub>1A</sub> receptor signaling.

Psychopharmacology·2026
Same journal

Fentanyl decreases arterial blood oxygen saturation more than furanylfentanyl in mice due to increased apnea.

Psychopharmacology·2026
Same journal

Suicide attempt risk among patients receiving methylphenidate: a retrospective cohort study.

Psychopharmacology·2026
Same journal

Investigating the impact of serotonergic psychedelic drugs, MDMA and ketamine on social cognition in psychiatric disorders: A scoping review.

Psychopharmacology·2026
Same journal

OPRD1 rs4654327 and Outcomes of Extended-Release Naltrexone in Alcohol Use Disorder: An Exploratory Prospective Pharmacogenetic Study.

Psychopharmacology·2026
See all related articles

This review explores how serotonin impacts cognition, learning, and memory. It discusses age-related changes in brain serotonin and potential pharmacologic treatments for age-associated memory loss.

Area of Science:

  • Neuroscience
  • Pharmacology

Background:

  • Serotonin is a neurotransmitter involved in numerous central nervous system functions, including cognition.
  • Alterations in the serotonergic system are observed in Alzheimer's disease and may occur with normal aging.

Purpose of the Study:

  • To review the role of serotonin in learning and memory.
  • To examine the effects of aging on brain serotonin function.
  • To discuss pharmacologic strategies for age-related memory impairments.

Main Methods:

  • Literature review and discussion of existing data.

Main Results:

  • Serotonin plays a role in cognitive functions like learning and memory.
  • Aging affects brain serotonin function, potentially contributing to memory decline.

Related Experiment Videos

Conclusions:

  • Understanding serotonin's role in aging-related cognitive changes is crucial for developing effective treatments.
  • Pharmacologic interventions targeting the serotonergic system may help mitigate memory impairments associated with aging.