Related Experiment Videos
The association of age with aspirin esterase activity in human liver
C Yelland1, J Summerbell, E Nicholson
1Department of Medicine (Geriatrics), The University, Newcastle upon Tyne.
Age and Ageing
|January 1, 1991
Abstract:
The activity of the phase 1 enzyme aspirin esterase was studied in liver tissue from 16 patients, aged 45-88 years. No correlation between age and enzyme activity was found in post-mitochondrial, cytosolic and microsomal fractions. These results provide further evidence that age is not a major determinant of the activity of hepatic drug-metabolizing enzymes in man.