[Fungal peritonitis during continuous ambulatory peritoneal dialysis (CAPD)]

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Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis
07:11

Surgical Techniques for Catheter Placement and 5/6 Nephrectomy in Murine Models of Peritoneal Dialysis

Published on: July 19, 2018

P García-Martos1, J Díaz Portillo, M A Pérez Ruilópez

  • 1Seccion de Microbiología, Hospital del SAS, Cádiz.

Enfermedades Infecciosas Y Microbiologia Clinica
|January 1, 1991
PubMed

Insights

Fungal peritonitis is a rare complication in continuous ambulatory peritoneal dialysis (CAPD) patients. Early diagnosis via culture and antifungal treatment are crucial for managing this infection.

Area of Science:

  • Nephrology
  • Infectious Diseases
  • Mycology

Context:

  • Continuous ambulatory peritoneal dialysis (CAPD) is a common treatment for end-stage renal disease.
  • Peritonitis is a known complication of CAPD, with bacterial infections being most common.
  • Fungal peritonitis is a less frequent but serious complication, particularly in long-term catheterized patients with prior antibiotic exposure.

Purpose:

  • To report three cases of fungal peritonitis in CAPD patients.
  • To highlight the incidence, diagnosis, and management of fungal peritonitis in this population.
  • To discuss the causative agents and outcomes of fungal peritonitis.

Summary:

  • Three cases of fungal peritonitis occurred over an 8-year period in 228 CAPD episodes (1.3% incidence).
  • Patients had long-term catheterization, previous bacterial peritonitis, and antibiotic therapy.
  • Diagnosis was confirmed by culture; treatment involved catheter exchange and antifungal agents, leading to infection resolution, though patients later died from unrelated causes. One case involved Candida lusitaniae.

Impact:

  • This study underscores the importance of considering fungal etiologies in CAPD peritonitis, especially in high-risk patients.
  • Culture-based diagnosis and prompt antifungal therapy are vital for successful management.
  • While fungal peritonitis can be treated, patient outcomes are influenced by underlying conditions and comorbidities.

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