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Updated: Jun 14, 2026

A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time
Published on: February 14, 2017
Cytokines, platelet production and hemostasis
1Room 271 College of Health Building, University of Oklahoma Health Sciences Center, P.O. Box 26901, Oklahoma City, OK, 73190, USA.
A number of hematopoietic growth factors and other cytokines are capable of altering platelet production and function. Enhancement of these processes may be exploited to ameliorate bleeding propensity in thrombocytopenic patients. Under certain circumstances, cytokines may have adverse effects on the hemostatic system, potentially involved in thrombogenesis and atherogenesis. Inhibition of those cytokines may prove to be a useful experimental approach to investigate their potential pathophysiologic role.
A number of hematopoietic growth factors and other cytokines are capable of altering platelet production and function. Enhancement of these processes may be exploited to ameliorate bleeding propensity in thrombocytopenic patients. Under certain circumstances, cytokines may have adverse effects on the hemostatic system, potentially involved in thrombogenesis and atherogenesis. Inhibition of those cytokines may prove to be a useful experimental approach to investigate their potential pathophysiologic role.
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