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Updated: Aug 11, 2026
07:44
Retroductal Submandibular Gland Instillation and Localized Fractionated Irradiation in a Rat Model of Salivary Hypofunction
Published on: April 24, 2016
Submandibular gland tumors
Plastic and Reconstructive Surgery
|February 1, 1978
Summary
Malignant tumors of the submandibular gland are rare but have a poor prognosis. Recommended treatment includes composite resections and selective postoperative radiation for better patient survival rates.
Area of Science:
- Oncology
- Head and Neck Surgery
- Salivary Gland Pathology
Background:
- Submandibular gland tumors are uncommon.
- Malignancy incidence in submandibular tumors approaches 50%, significantly higher than parotid gland tumors.
- The 5-year survival rate for malignant submandibular tumors is poor (28%) compared to parotid tumors (71.8%).
Purpose of the Study:
- To highlight the poor prognosis of malignant submandibular gland tumors.
- To recommend optimal surgical and adjuvant treatment strategies.
- To improve survival outcomes for patients with these rare malignancies.
Main Methods:
- Retrospective analysis of submandibular gland tumor cases.
- Comparison of survival rates between submandibular and parotid gland tumors.
- Evaluation of treatment modalities including composite resection and postoperative radiation.
Main Results:
- Malignant submandibular gland tumors demonstrate a significantly lower 5-year survival rate.
- Composite resection is advised for most submandibular tumors, excluding low-grade mucoepidermoid types.
- Postoperative radiation therapy is indicated based on specific prognostic factors.
Conclusions:
- Malignant submandibular gland tumors necessitate aggressive surgical management.
- Tailored postoperative radiation is crucial for specific patient groups.
- Improved treatment strategies are essential to enhance survival for this challenging condition.
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