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Fishing for age-related visual system mutants: behavioral screening of retinal degeneration genes in zebrafish
Lei Li1, Yuhao Li, Dongyan Chen
1Department of Physiology, Nankai University School of Medicine, Tianjin, China. Li.78@nd.edu
Current Aging Science
|March 20, 2010
Abstract:
The zebrafish (Danio rerio) has recently become a mainstream model system for genetic studies of human diseases, such as neurological degenerative diseases, heart diseases, immuno-system disorders, etc. In this article, we will review some recent findings of the usefulness of zebrafish as a model vertebrate for behavioral screening of mutations in vertebrate visual system, for example, genes involved in age-related retinal degeneration.
